|
Quartz Crystal
Microbalance QCMagic ( QCM) |
|

The
Quartz Crystal Microbalance
QCMagic (QCM) set-up has been designed to directly drive piezoelectric transducers. It consists of single/multiple measuring units, driven by a
USB base unit, suitable for:
-
biosensor development
-
affinity reaction studies
-
association/dissociation and kinetic constants determination
-
monoclonal antibodies characterization
-
binding site mapping
-
DNA hybridization
-
analysis of electrochemical deposition, polymers coated on electrodes, corrosion, adsorption and electrochemical reaction mechanisms
-
multi-probing detection
|
|
QCMagic
is a high precision measuring instrument featuring excellent
performance in the recovery of the oscillation frequency of a
working quartz crystal.The system is interfaced to the driving
PC by means of the USB port. One single Base Unit can drive up
to 4 oscillator modules, thus allowing to operate with up to 4
independent quartz crystals (or with two pairs of
working/reference crystals). QCMagic can be equipped with
low-volume static or flow-through reaction chambers, which house
the oscillating crystal; fitting the transducer into the
different type of cells is rapid and convenient. QCMagic makes
use of a precision internal reference crystal, used as a
timebase comparator. Depending on the frequency of this internal
timebase, each Unit can be tuned to work with a specific working
crystal, choosen between 1 and 10 MHz. The Oscillator Modules
are connected to the Base Unit by means of a RJ45 cable carrying
both power supply and signals.
[click on the images to enlarge]
|
|
|
|
QCMagic
is interfaced with a personal computer by USB port for data
acquisition and storage. The system is driven by an extremely
user-friendly software running under MS-WindowsTM. It consist of
a lower level kernel which implements the necessary data
transfer between the computer and the unit(s), and of a high
level set of routines which drive the user through an easy to
perform data acquisition and analysis. In addition to the data
acquisition service routine, an useful data display has been
implemented by which the user can easily retrieve the acquired
signal levels. Oscillating frequency versus time measurements
can be performed following the data acqusition in real time on
the computer screen, by means of strip chart plotting.

|
|
Max resolution (gate dependent) ±0.05 Hz |
|
Gate interval 0.01 to 10 s |
|
Frequency stability 100 ppm/°C |
|
Counter logic 32 bit |
|
Air oscillator TTL compatible |
|
Liquid oscillator TTL compatible |
|
Interface USB port |
|
Instrument output delta f (proportional to electrode mass) |
|
Biochemical output analyte concentration |
|
Transducer quartz crystal AT-cut,
9.5 MHz (standard)1 to 10 MHz (optional) |
|
Units 1 to 4 |
|
Crystal port standard 125
mm |
|
Warm-up interval 30-40 min (only after first power-up to meet above stability specifications) |
|
Software Real time frequency data via dedicated software (windows application running under Win 9x, NT, 2000, XP,
Vista) |
|
Physical dimensions(base Unit) 165 x 35 x 65 mm (L x H x W) |
|
Power supply external +12
Vdc |
|
Operating temperature 0° to 55°C |
|
|
|
Optionally
we can provide an additional software tool "QCMath" allowing a
mathematical analysis on acquired data or on any .xls (Microsoft
Excel) data file.
QCMath allows these fittings:
-
Linear FittingOne Site Binding
-
Sigmoidal Dose Response
-
Sigmoidal Dose Response variable slope
-
One Site Competition
-
One Phase Exponential Decay
-
Two Phase Exponential Decay
-
One Phase Exponential Association
-
Polynomial 1° order
-
Polynomial 2° order
-
Polynomial 3° order
-
Polynomial 4° order
|